Internet-Supported Physical Exercise Training for Persons with Multiple Sclerosis—A Randomised, Controlled Study

International Journal of Molecular Sciences

Mathias Mäurer¹  Alexander Tallner²  René Streber²  Marc Morgott²  Wolfgang Geidl²  Klaus Pfeifer²  Christian Hentschke² 

[1] Department of Neurology, Stiftung Juliusspital, 97070 Würzburg, Germany;Division Exercise and Health, Institute of Sport Science and Sport, Friedrich-Alexander-Universität Erlangen-Nürnberg, 91058 Erlangen, Germany;

关键词: multiple sclerosis;    internet;    telerehabilitation;    resistance training;    aerobic training;    exercise;    physical activity;    health-related quality of life;    fatigue;    lung function;   

DOI  :  10.3390/ijms17101667

来源: DOAJ

【 摘 要 】

Physical exercise is effective in improving functional outcomes in persons with multiple sclerosis (pwMS). We evaluated the feasibility and effectiveness of internet-based exercise training (e-training) for pwMS on health-related quality of life (HrQoL). Secondary outcomes were muscle strength, aerobic capacity, lung function, physical activity, and fatigue. This is a randomised, controlled trial with a wait-list control group. Data were collected at baseline, after three and six months, and analysed using a hybrid linear model. One-hundred twenty-six pwMS participated in the home-based aerobic (1×/week) and strength training (2×/week) intervention that was supervised and documented via an internet-platform. The intervention group received e-training for six months, and the control group received e-training after a three months waiting period. Significant differences between the groups were only observed for muscle strength (knee flexion (effect size ES = 0.3, p = 0.003), knee extension (ES = 0.24, p = 0.015)), peak expiratory flow (ES = 0.2, p = 0.039), and sports activity (ES = 0.33, p = 0.001) after three months. E-training had no effect on HrQoL but did on muscle strength, lung function, and physical activity. It is a promising and feasible approach to facilitate large-scale, yet individual, training support.

【 授权许可】

Unknown