Magnetic Molecularly Imprinted Nano-Conjugates for Effective Extraction of Food Components—A Model Study of Tyramine Determination in Craft Beers

International Journal of Molecular Sciences

Joanna Giebułtowicz¹  Marta Janczura²  Monika Sobiech²  Piotr Luliński² 

[1] Department of Bioanalysis and Drugs Analysis, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland;Department of Organic Chemistry, Faculty of Pharmacy, Medical University of Warsaw, Banacha 1, 02-097 Warsaw, Poland;

关键词: magnetic molecularly imprinted polymers;    dispersive solid phase extraction;    tyramine;    craft beer;    biogenic amine;    liquid chromatography coupled with tandem mass spectrometry;   

DOI  :  10.3390/ijms22179560

来源: DOAJ

【 摘 要 】

In this paper, magnetic molecularly imprinted nano-conjugates were synthesized to serve as selective sorbents in a model study of tyramine determination in craft beer samples. The molecularly imprinted sorbent was characterized in terms of morphology, structure, and composition. The magnetic dispersive solid phase extraction protocol was developed and combined with liquid chromatography coupled with mass spectrometry to determine tyramine. Ten samples of craft beers were analyzed using a validated method, revealing tyramine concentrations in the range between 0.303 and 126.5 mg L⁻¹. Tyramine limits of detection and quantification were 0.033 mg L⁻¹ and 0.075 mg L⁻¹, respectively. Therefore, the fabricated molecularly imprinted magnetic nano-conjugates with a fast magnetic responsivity and desirable adsorption performance could be an effective tool for monitoring tyramine levels in beverages.

【 授权许可】

Unknown