Plants | |
Exploring the Phytochemicals of Acacia melanoxylon R. Br. | |
Cecília M. P. Rodrigues1  Joana Gonçalves1  Sidónio Duarte2  Ana Lourenço2  Patrícia Máximo2  Diana Alves2  Pedro Arsénio3  | |
[1] Faculty of Pharmacy, Research Institute for Medicines (iMed.ULisboa), Universidade de Lisboa, Av. Prof. Gama Pinto, 1649-003 Lisbon, Portugal;LAQV-REQUIMTE, Department of Chemistry, NOVA School of Science and Technology, NOVA University, 2829-516 Caparica, Portugal;Linking Landscape, Environment, Agriculture and Food (LEAF)—Research Center, Associated Laboratory TERRA, Instituto Superior de Agronomia, Universidade de Lisboa, Tapada da Ajuda, 1349-017 Lisbon, Portugal; | |
关键词: invasive species; Acacia melanoxylon; terpenoids; HCT116 human colorectal cancer cells; cytotoxicity; | |
DOI : 10.3390/plants10122698 | |
来源: DOAJ |
【 摘 要 】
Invasive species are currently a world menace to the environment, although the study of their chemistry may provide a means for their future beneficial use. From a study of Portuguese Acacia melanoxylon R. Br. five known compounds were isolated: lupeol, 3β-Z-coumaroyl lupeol, 3β-E-coumaroyl lupeol (dioslupecin A), kolavic acid 15-methyl ester and vomifoliol (blumenol A). Their structures were elucidated by 1D and 2D NMR spectroscopy and mass spectrometry, and as a result some corrections are made to their previous 13C NMR assignments. Cytotoxicity of 3β-E-coumaroyl lupeol (dioslupecin A) and kolavic acid 15-methyl ester was evaluated against HCT116 human colorectal cancer cells although biological activity was not evident.
【 授权许可】
Unknown