The Medicinal Natural Products of Cannabis sativa Linn.: A Review

Molecules

Anwuli Endurance Odieka¹  Adebola Omowunmi Oyedeji¹  Opeoluwa Oyehan Oyedeji²  Yiseyon Sunday Hosu³  Mavuto Gondwe⁴  Gloria Ukalina Obuzor⁵ 

[1] Department of Chemical and Physical Sciences, Walter Sisulu University, Mthatha 5099, South Africa;Department of Chemistry, Fort Hare University, Alice 5700, South Africa;Department of Economics and Business Sciences, Walter Sisulu University, Mthatha 5099, South Africa;Department of Human Biology, Walter Sisulu University, Mthatha 5099, South Africa;Department of Pure and Industrial Chemistry, University of Port Harcourt, Port Harcourt 500004, Rivers State, Nigeria;

关键词: medicinal plant;    Cannabis sativa;    phytochemicals;    bioactivity;    extraction methods;    characterization;   

DOI  :  10.3390/molecules27051689

来源: DOAJ

【 摘 要 】

Cannabis sativa is known among many cultures for its medicinal potential. Its complexity contributes to the historical application of various parts of the plant in ethno-medicines and pharmacotherapy. C. sativa has been used for the treatment of rheumatism, epilepsy, asthma, skin burns, pain, the management of sexually transmitted diseases, difficulties during child labor, postpartum hemorrhage, and gastrointestinal activity. However, the use of C. sativa is still limited, and it is illegal in most countries. Thus, this review aims to highlight the biological potential of the plant parts, as well as the techniques for the extraction, isolation, and characterization of C. sativa compounds. The plant produces a unique class of terpenophenolic compounds, called cannabinoids, as well as non-cannabinoid compounds. The exhaustive profiling of bioactive compounds and the chemical characterization and analysis of C. sativa compounds, which modern research has not yet fully achieved, is needed for the consistency, standardization, and the justified application of Cannabis sativa products for therapeutic purposes. Studies on the clinical relevance and applications of cannabinoids and non-cannabinoid phenols in the prevention and treatment of life-threatening diseases is indeed significant. Furthermore, psychoactive cannabinoids, when chemically standardized and administered under medical supervision, can be the legal answer to the use of C. sativa.

【 授权许可】

Unknown