The Global Emergency of Novel Coronavirus (SARS-CoV-2): An Update of the Current Status and Forecasting

International Journal of Environmental Research and Public Health

René Roy¹  Leila Mousavifar¹  FrancescaPiceci Sparascio²  Hossein Hozhabri²  Daniela Scribano³  Meysam Sarshar⁴  Hamidreza Sohrabi⁵  Cecilia Ambrosi⁶  Alessandro De Luca⁷ 

[1] Department of Chemistry, Université du Québec à Montréal, P.O. Box 8888, Succ. Centre-Ville, Montréal, QC H3C 3P8, Canada;Department of Experimental Medicine, Sapienza University of Rome, 00161 Rome, Italy;Department of Public Health and Infectious Diseases, Sapienza University of Rome, 00185 Rome, Italy;Department of Public Health and Infectious Diseases, Sapienza University of Rome, Laboratory affiliated to Institute Pasteur Italia- Cenci Bolognetti Foundation, 00185 Rome, Italy;Department of Veterinary Science, University of Turin, 10095 Grugliasco, Italy;IRCCS San Raffaele Pisana, Department of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, 00166 Rome, Italy;Medical Genetics Division, Fondazione IRCCS Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, Italy;

关键词: SARS-CoV-2;    epidemiology;    transmission;    temperature and humidity;    COVID-19;    pneumonia;   

DOI  :  10.3390/ijerph17165648

来源: DOAJ

【 摘 要 】

Over the past two decades, there have been two major outbreaks where the crossover of animal Betacoronaviruses to humans has resulted in severe acute respiratory syndrome coronavirus (SARS-CoV) and Middle East respiratory syndrome coronavirus (MERS-CoV). In December 2019, a global public health concern started with the emergence of a new strain of coronavirus (SARS-CoV-2 or 2019 novel coronavirus, 2019-nCoV) which has rapidly spread all over the world from its origin in Wuhan, China. SARS-CoV-2 belongs to the Betacoronavirus genus, which includes human SARS-CoV, MERS and two other human coronaviruses (HCoVs), HCoV-OC43 and HCoV-HKU1. The fatality rate of SARS-CoV-2 is lower than the two previous coronavirus epidemics, but it is faster spreading and the large number of infected people with severe viral pneumonia and respiratory illness, showed SARS-CoV-2 to be highly contagious. Based on the current published evidence, herein we summarize the origin, genetics, epidemiology, clinical manifestations, preventions, diagnosis and up to date treatments of SARS-CoV-2 infections in comparison with those caused by SARS-CoV and MERS-CoV. Moreover, the possible impact of weather conditions on the transmission of SARS-CoV-2 is also discussed. Therefore, the aim of the present review is to reconsider the two previous pandemics and provide a reference for future studies as well as therapeutic approaches.

【 授权许可】

Unknown