Effect of urea and tmao on lipid bilayers

European Pharmaceutical Journal

Bernstorff S.¹  Funari S.S.²  Valerio J.² 

[1] Elettra-Sincrotrone Trieste S.C.p.A, Trieste, Italy;Photo Science at DESY, Hamburg, Germany;

关键词: lipid membranes - phase transitions - osmocytes - x-rays - dsc;   

DOI  :  10.1515/afpuc-2017-0003

来源: DOAJ

【 摘 要 】

We study the effect of the osmolytes, Urea and trimethylamine-N-oxide (TMAO) on POPE (1-palmitoyl-2-oleoyl-sn-glycero-3- phosphoethanolamine) lipid membranes using SAXS/WAXS and DSC. Their antagonist effect is observed with TMAO stabilizing and Urea destabilizing the lipid bilayer, as seen by others in earlier researches.

【 授权许可】

Unknown