Effect of State Legislation on Discharge Opioid Prescriptions After Total Hip and Knee Arthroplasties

Arthroplasty Today

Keli K. Doe, BS¹  Gregory J. Golladay, MD²  Charles P. Benfield, MD³  Leroy R. Thacker, PhD³  Omar A. Protzuk, MD⁴ 

[1] Corresponding author. Department of Orthopaedic Surgery, Virginia Commonwealth University Medical Center, 1200 East Broad Street, 9th Floor, Box 980153, Richmond, VA 23298-0153, USA. Tel.: [phone].;Department of Biostatistics, Virginia Commonwealth University, Richmond, VA, USA;Department of Orthopaedic Surgery, Virginia Commonwealth University Health System, Richmond, VA, USA;Virginia Commonwealth University School of Medicine, Richmond, VA, USA;

关键词: Opioid;    Arthroplasty;    Prescription;    Legislation;   

DOI  :  

来源: DOAJ

【 摘 要 】

Background: Recent literature suggests that state-level legislation is effective in reducing postoperative opioid prescribing after total joint arthroplasty but has not addressed the effect on opioid antagonist coprescribing. This study aims to describe the change in postoperative opioid and opioid antagonist prescribing patterns after total joint arthroplasty following passage of state-level opioid-limiting legislation and to determine the comorbidities associated with increased opioid prescribing in this population. Methods: Billing data were used to identify all patients who underwent primary total hip or knee arthroplasty admitted between March 2016 and March 2018 at our institution. The data were divided into 2 cohorts comprising the year before (671 subjects) and after (713 subjects) the legislation. Discharge prescriptions were reviewed, and the median morphine milligram equivalents (MME) per day and naloxone prescriptions were recorded. International Classification of Diseases codes were used to identify comorbid conditions of interest present during previous inpatient or outpatient encounters. Results: There was a significant reduction in both the minimum and maximum median MME per day after introduction of state legislation and a substantial increase in opioid antagonist coprescription. Total knee arthroplasty, younger age, male sex, chronic pain disorders, post-traumatic stress disorder, and prior opioid abuse were correlated with increased opioid prescribing. Conclusion: Our findings suggest that state-level legislation is effective in decreasing the MME per day prescribed and increasing opioid antagonist coprescription in the postoperative period for patients undergoing total hip and knee arthroplasties at our institution. These changes may lead to a decrease in opioid-related morbidity and mortality in the patient population undergoing total hip and knee arthroplasties.

【 授权许可】

Unknown