Synthesis, Spectral and Antibacterial Studies of Copper(II) Tetraaza Macrocyclic Complexes

International Journal of Molecular Sciences

关键词: synthesis;    antibacterial studies;    tetraaza macrocycles;    copper(II) complexes;   

DOI  :  10.3390/ijms13044982

来源: DOAJ

【 摘 要 】

A novel family of tetraaza macrocyclic Cu(II) complexes [CuLX₂] (where L = N₄ donor macrocyclic ligands) and (X = Cl⁻, NO₃⁻) have been synthesized and characterized by elemental analysis, magnetic moments, IR, EPR, mass, electronic spectra and thermal studies. The magnetic moments and electronic spectral studies suggest square planar geometry for [Cu(DBACDT)]Cl₂ and [Cu(DBACDT)](NO₃)₂ complexes and distorted octahedral geometry to the rest of the ten complexes. The biological activity of all these complexes against gram-positive and gram-negative bacteria was compared with the activity of existing commercial antibacterial compounds like Linezolid and Cefaclor. Six complexes out of twelve were found to be most potent against both gram-positive as well as gram-negative bacteria due to the presence of thio group in the coordinated ligands.

【 授权许可】

Unknown