International Journal of Molecular Sciences | |
Synthesis, Spectral and Antibacterial Studies of Copper(II) Tetraaza Macrocyclic Complexes | |
关键词: synthesis; antibacterial studies; tetraaza macrocycles; copper(II) complexes; | |
DOI : 10.3390/ijms13044982 | |
来源: DOAJ |
【 摘 要 】
A novel family of tetraaza macrocyclic Cu(II) complexes [CuLX2] (where L = N4 donor macrocyclic ligands) and (X = Cl−, NO3−) have been synthesized and characterized by elemental analysis, magnetic moments, IR, EPR, mass, electronic spectra and thermal studies. The magnetic moments and electronic spectral studies suggest square planar geometry for [Cu(DBACDT)]Cl2 and [Cu(DBACDT)](NO3)2 complexes and distorted octahedral geometry to the rest of the ten complexes. The biological activity of all these complexes against gram-positive and gram-negative bacteria was compared with the activity of existing commercial antibacterial compounds like Linezolid and Cefaclor. Six complexes out of twelve were found to be most potent against both gram-positive as well as gram-negative bacteria due to the presence of thio group in the coordinated ligands.
【 授权许可】
Unknown