Accuracy in detecting inadequate research reporting by early career peer reviewers using an online CONSORT-based peer-review tool (COBPeer) versus the usual peer-review process: a cross-sectional diagnostic study

BMC Medicine

Alessandro Recchioni¹  David Moher²  Douglas G. Altman³  Sally Hopewell³  Daniel Shanahan⁴  Valeria Martinez⁵  David Schriger⁶  Laurence Le Cleach⁷  Sabina Alam⁸  Philippe Ravaud⁹  Carolina Riveros⁹  Gabriel Baron⁹  Jean-Philippe Regnaux⁹  Anthony Chauvin⁹  Isabelle Boutron⁹  Perrine Crequit⁹ 

[1] BMC Medicine;Centre for Journalology, Ottawa Hospital Research Institute, School of Epidemiology and Public Health, University of Ottawa;Centre for Statistics in Medicine, University of Oxford;Cochrane Central Executive;Department of Anesthesiology, Assistance Publique Hôpitaux de Paris, Hôpital Raymond Poincaré;Department of Emergency Medicine, School of Medicine, University of California;Service de Dermatologie, Hopital Mondor, Assistance Publique des Hôpitaux de Paris, Université Paris Est Creteil, EpidermE;Taylor and Francis group;Université de Paris, CRESS, Inserm, INRA;

关键词: Peer reviewers;    Randomized controlled trials;    Reporting;    CONSORT statement;   

DOI  :  10.1186/s12916-019-1436-0

来源: DOAJ

【 摘 要 】

Abstract Background The peer review process has been questioned as it may fail to allow the publication of high-quality articles. This study aimed to evaluate the accuracy in identifying inadequate reporting in RCT reports by early career researchers (ECRs) using an online CONSORT-based peer-review tool (COBPeer) versus the usual peer-review process. Methods We performed a cross-sectional diagnostic study of 119 manuscripts, from BMC series medical journals, BMJ, BMJ Open, and Annals of Emergency Medicine reporting the results of two-arm parallel-group RCTs. One hundred and nineteen ECRs who had never reviewed an RCT manuscript were recruited from December 2017 to January 2018. Each ECR assessed one manuscript. To assess accuracy in identifying inadequate reporting, we used two tests: (1) ECRs assessing a manuscript using the COBPeer tool (after completing an online training module) and (2) the usual peer-review process. The reference standard was the assessment of the manuscript by two systematic reviewers. Inadequate reporting was defined as incomplete reporting or a switch in primary outcome and considered nine domains: the eight most important CONSORT domains and a switch in primary outcome(s). The primary outcome was the mean number of domains accurately classified (scale from 0 to 9). Results The mean (SD) number of domains (0 to 9) accurately classified per manuscript was 6.39 (1.49) for ECRs using COBPeer versus 5.03 (1.84) for the journal’s usual peer-review process, with a mean difference [95% CI] of 1.36 [0.88–1.84] (p < 0.001). Concerning secondary outcomes, the sensitivity of ECRs using COBPeer versus the usual peer-review process in detecting incompletely reported CONSORT items was 86% [95% CI 82–89] versus 20% [16–24] and in identifying a switch in primary outcome 61% [44–77] versus 11% [3–26]. The specificity of ECRs using COBPeer versus the usual process to detect incompletely reported CONSORT domains was 61% [57–65] versus 77% [74–81] and to identify a switch in primary outcome 77% [67–86] versus 98% [92–100]. Conclusions Trained ECRs using the COBPeer tool were more likely to detect inadequate reporting in RCTs than the usual peer review processes used by journals. Implementing a two-step peer-review process could help improve the quality of reporting. Trial registration Clinical.Trials.gov NCT03119376 (Registered April, 18, 2017).

【 授权许可】

Unknown