Homozygous familial hypercholesterolemia with stenosis of the left anterior descending coronary artery successfully treated with weekly low‐density lipoprotein apheresis for 16 years without percutaneous coronary intervention

Clinical Case Reports

Shigeru Toyoda¹  Atsuhiko Kawabe²  Masahiro Shimoyama²  Takushi Sugiyama²  Takanori Yasu²  Tomohiro Iwakura³  Hiroshi Wada⁴ 

[1] Department of Cardiovascular Medicine Dokkyo Medical University Mibu Japan;Department of Cardiovascular Medicine and Nephrology Dokkyo Medical University Nikko Medical Center Nikko Japan;Department of Cardiovascular Surgery Sakakibara Heart Institute Tokyo Japan;Department of First Integrated Medicine 1, Saitama Medical Center Jichi Medical University Saitama Japan;

关键词: angina;    apheresis;    homozygous familial hypercholesterolemia;    iodine allergy;   

DOI  :  10.1002/ccr3.2299

来源: DOAJ

【 摘 要 】

Abstract We successfully treated a patient with homozygous familial hypercholesterolemia (HoFH) with stable coronary arterial disease using optimal medical therapy and low‐density lipoprotein (LDL) apheresis for 16 years without percutaneous coronary intervention or bypass surgery. Intensive LDL lowering using apheresis and medication protected the patient from coronary atherosclerotic progression even in HoFH.

【 授权许可】

Unknown