Ypsilandrosides U-Y, five new steroidal saponins from Ypsilandra thibetica

Natural Products and Bioprospecting

Wen-Tao Gao¹  Wen-Yi Ma²  Long-Gao Xiao²  Ling-Ling Yu²  Shi-Juan Zhang²  Jing Xie²  Huan Yan²  Hai-Yang Liu² 

[1] College of Traditional Chinese Medicine, Yunnan University of Chinese Medicine;State Key Laboratory of Phytochemistry and Plant Resources in West China, and Yunnan Key Laboratory of Natural Medicinal Chemistry, Kunming Institute of Botany, Chinese Academy of Sciences;

关键词: Ypsilandra thibetica;    Melanthiaceae;    Ypsilandrosides U-Y;    Spirostanol saponins;    Cholestanol saponins;   

DOI  :  10.1007/s13659-022-00337-0

来源: DOAJ

【 摘 要 】

Abstract Phytochemical reinvestigation on the whole plants of Ypsilandra thibetica obtained four new spirostanol glycosides, named ypsilandrosides U-X (1–4), and one new cholestanol glycoside, named ypsilandroside Y (5). Their structures have been established by extensive spectroscopic data and chemical methods. Among them, compound 4 is a rare spirostanol glycoside which possesses a novel 5(6 → 7) abeo-steroidal aglycone, while compound 1 is a first spirostanol bisdesmoside attached to C-3 and C-12, respectively, isolated from the genus Ypsilandra. The induced platelet aggregation activity of the isolates was tested. Graphical Abstract

【 授权许可】

Unknown