MR-Guided Radiotherapy for Prostate Cancer

Frontiers in Oncology

Alison C. Tree¹  Boris R. Tocco²  Linda G. W. Kerkmeijer³  Ting Martin Ma⁴  Amar U. Kishan⁴ 

[1] Department of Radiotherapy and Imaging, Institute of Cancer Research, London, United Kingdom;Department of Radiotherapy, The Royal Marsden NHS Foundation Trust, London, United Kingdom;Radboud University Medical Center, Nijmegen, Netherlands;University of California, Los Angeles, Los Angeles, CA, United States;

关键词: prostate cancer;    MR-linac;    image-guided radiotherapy;    online adaptive radiotherapy;    MR-guided radiotherapy;   

DOI  :  10.3389/fonc.2020.616291

来源: DOAJ

【 摘 要 】

External beam radiotherapy remains the primary treatment modality for localized prostate cancer. The radiobiology of prostate carcinoma lends itself to hypofractionation, with recent studies showing good outcomes with shorter treatment schedules. However, the ability to accurately deliver hypofractionated treatment is limited by current image-guided techniques. Magnetic resonance imaging is the main diagnostic tool for localized prostate cancer and its use in the therapeutic setting offers anatomical information to improve organ delineation. MR-guided radiotherapy, with daily re-planning, has shown early promise in the accurate delivery of radiotherapy. In this article, we discuss the shortcomings of current image-guidance strategies and the potential benefits and limitations of MR-guided treatment for prostate cancer. We also recount present experiences of MR-linac workflow and the opportunities afforded by this technology.

【 授权许可】

Unknown