Infection Prevention in Practice | |
Antibiotic Prescribing Patterns at COVID-19 Dedicated Wards in Bangladesh: Findings from a Single Center Study | |
Mahmuda Yeasmin1  Md. Masum Hossain Arif2  Monira Parveen3  Tasnim Nafisa3  Md. Robed Amin3  Md. Mohiuddin Sharif3  Syed Jafar Raza Rizvi3  Junaid Abdullah Jamiul Alam4  Arifa Akram5  K.M. Saif-Ur-Rahman6  Md. Maruf Ahmed Molla7  Md. Khairul Islam7  A.K.M. Shamsuzzaman7  Asish Kumar Ghosh7  | |
[1] Corresponding author. Department of Virology, National Institute of Laboratory Medicine and Referral Center, Bangladesh. Tel.: +8801711447858.;Dhaka Dental College, Dhaka, Bangladesh;Dhaka Medical College and Hospital, Dhaka, Bangladesh;Evercare Hospital, Dhaka, Bangladesh;Health Systems and Population Studies Division, icddr,b, Dhaka, Bangladesh;Johns Hopkins University, Center for Communication Programs, Dhaka, Bangladesh;National Institute of Laboratory Medicine and Referral Center, Dhaka, Bangladesh; | |
关键词: COVID-19; Antimicrobial resistance; Bangladesh; SARS-CoV-2; Point prevalence survey; | |
DOI : | |
来源: DOAJ |
【 摘 要 】
Summary:Background: As evidence is mounting regarding irrational and often unnecessary use of antibiotics during the COVID-19 pandemic a cross-sectional Point Prevalence Survey (PPS) (in accordance with WHO guideline) was conducted across COVID-19 dedicated wards in Dhaka Medical College and Hospital (DMCH). Methodology: Antibiotic usage data were collected from 193 patients at different COVID-19 dedicated wards at DMCH on 11 June 2020. Comparisons in antibiotic usage were made between different groups using Pearson chi-square and Fisher's exact test. Result: Findings reveal all surveyed patients (100%) were receiving at least one antibiotic with 133 patients (68.91%) receiving multiple antibiotics. Overall, patients presenting with the severe disease received more antibiotics. Third-generation cephalosporins (i.e. ceftriaxone) (53.8%), meropenem (40.9%), moxifloxacin (29.5%), and doxycycline (25.4%) were the four most prescribed antibiotics among surveyed patients. Diabetes mellitus (DM) was independently associated with multiple antibiotic prescribing. Abnormal C-reactive protein (CRP) and serum d-dimer were linked with higher odds of multiple antibiotic prescribing among study patients. Conclusion: Prevalence of multiple antibiotic prescriptions was high among severely ill patients and those with abnormal CRP and d-dimer levels. Data regarding the quality of antibiotic prescribing were lacking.
【 授权许可】
Unknown