Association of Toll-like receptor 7 variants with life-threatening COVID-19 disease in males: findings from a nested case-control study

eLife

Francesca Mari¹  Maria Bandini²  Francesca Fava³  Serena Ludovisi³  Elisa Benetti⁴  Massimo Vaghi⁴  Katia Capitani⁴  Matteo Siano⁴  Sergio Daga⁴  Elisabetta Schiaroli⁵  Mario U Mondelli⁶  Elisa Frullanti⁷  Alessandra Renieri⁸  GEN-COVID Multicenter Study⁸  Francesco Paciosi⁹  Nicola Picchiotti^1,10  Simone Furini^1,10  Margherita Baldassarri^1,11  Francesco Castelli^1,11  Maria Palmieri^1,11  Daniela Francisci^1,12  Stefano Rusconi^1,13  Stefania Mantovani^1,13  Ottavia Spiga^1,13  Eugenia Quiros-Roldan^1,13  Chiara Fallerini^1,13 

[1] Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy;Genetica Medica, Azienda Ospedaliero-Universitaria Senese, Siena, Italy;Infectious Diseases Clinic, "Santa Maria" Hospital, University of Perugia, Perugia, Italy;Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy;University of Siena, DIISM-SAILAB, Siena, Italy;Chirurgia Vascolare, Ospedale Maggiore di Crema, Crema, Italy;Department of Biomedical and Clinical Sciences Luigi Sacco, University of Milan, Milan, Italy;Department of Infectious and Tropical Diseases, University of Brescia and ASST Spedali Civili Hospital, Brescia, Italy;Department of Mathematics, University of Pavia, Pavia, Italy;Division of Infectious Diseases and Immunology, Department of Medical Sciences and Infectious Diseases, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy;Infectious Diseases Clinic, Department of Medicine 2, Azienda Ospedaliera di Perugia and University of Perugia, Santa Maria Hospital, Perugia, Italy;Med Biotech Hub and Competence Center, Department of Medical Biotechnologies, University of Siena, Siena, Italy;Medical Genetics, University of Siena, Siena, Italy;

关键词: TLR7;    COVID-19;    LASSO Logistic Regression Analysis;   

DOI  :  10.7554/eLife.67569

来源: DOAJ

【 授权许可】

Unknown