Discussions and perspectives regarding oxytocin as a biomarker in human investigations

Heliyon

Melissa Andrea Cárdenas Molano¹  Juan Carlos Caicedo Mera²  Cristina Acevedo Triana³  Jorge Martínez Cotrina³  Christian Camilo García López³ 

[1] Laboratorio Interdisciplinar de Ciencias y Procesos Humanos LINCIPH, Facultad de Ciencias Sociales y Humanas, Universidad Externado de Colombia, Colombia;Corresponding author.;Laboratorio Interdisciplinar de Ciencias y Procesos Humanos LINCIPH, Facultad de Ciencias Sociales y Humanas, Universidad Externado de Colombia, Colombia;

关键词: Oxytocin;    Saliva;    ELISA;    RIA;    Social behavior;   

DOI  :  

来源: DOAJ

【 摘 要 】

This article introduces a review of research that has implemented oxytocin measurements in different fluids such as plasma, cerebrospinal fluid, urine and, mainly, saliva. The main purpose is to evaluate the level of evidence supporting the measurement of this biomarker implicated in a variety of psychological and social processes. First, a review of the technical developments that allowed the characterization, function establishing, and central and peripheral levels of this hormone is proposed. Then, the article approaches the current discussions regarding the level of reliability of the laboratory techniques that enable the measurement of oxytocin, focusing mainly on the determination of its concentration in saliva through Enzyme-Linked Immunosorbent Assay (ELISA). Finally, research results, which have established the major physiological correlates of this hormone in fields such as social neuroscience and neuropsychology, are collected and discussed in terms of the hormone measurement methods that different authors have used. In this way, the article is expected to contribute to the panorama of debates and current perspectives regarding investigation involving this important biomarker.

【 授权许可】

Unknown