期刊论文详细信息
Journal of Orthopaedic Surgery and Research
Topping-off surgery vs posterior lumbar interbody fusion for degenerative lumbar disease: a finite element analysis
Yunpeng Fan1  Liulong Zhu1  Zefeng Yu2  Xiao Han2  Shaobo Zhou2  Tao Xie2 
[1] Department of Orthopedic Surgery, The Affiliated Hangzhou Hospital of Nanjing Medical University;The Affiliated Hangzhou First People’s Hospital, Zhejiang University School of Medicine;
关键词: Coflex;    PLIF;    Adjacent segment disease;    ASD;    Finite element analysis;   
DOI  :  10.1186/s13018-019-1503-4
来源: DOAJ
【 摘 要 】

Abstract Background Adjacent segment disease (ASD) is a common complication after posterior lumbar interbody fusion (PLIF). Recently, a topping-off surgery (non-fusion with Coflex) has been developed to reduce the risk of ASD, yet whether and how the topping-off surgery can relieve ASD remains unclear. The purpose of this study was to explore the biomechanical effect of PLIF and Coflex on the adjacent segments via finite element (FE) analysis and discuss the efficacy of Coflex in preventing ASD. Methods A FE model of L3–L5 segments was generated based on the CT of a healthy volunteer via three commercially available software. Coflex and PLIF devices were modeled and implanted together with the segment model in the FE software. In the FE model, a pre-compressive load of 500 N, equal to two-thirds of the human body mass, was applied on the top surface of the L3. In addition, four types of moments (anteflexion, rear protraction, bending, and axial rotation) set as 10 Nm were successively applied to the FE model combined with this pre-compressive load. Then, the range of motion (ROM), the torsional rigidity, and the maximum von Mises equivalent stress on the L3–L4 intervertebral disc and the implant were analyzed. Results Both Coflex and PLIF reduced ROM. However, no significant difference was found in the maximum von Mises equivalent stress of adjacent segment disc between the two devices. Interestingly enough, both systems increased the torsional rigidity at the adjacent lumbar segment, and PLIF had a more significant increase. The Coflex implant had a larger maximum von Mises equivalent stress. Conclusions Both Coflex and PLIF reduced ROM at L3–L4, and thus improved the lumbar stability. Under the same load, both devices had almost the same maximum von Mises equivalent stress as the normal model on the adjacent intervertebral disc. But it is worthy to notice the torsional rigidity of PLIF was higher than that of Coflex, indicating that the lumbar treated with PLIF undertook a larger load to reach ROM of Coflex. Therefore, we presumed that ADS was related to a higher torsional rigidity.

【 授权许可】

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