期刊论文详细信息
Cells | |
The Mysterious Actor—γδ T Lymphocytes in Chronic Lymphocytic Leukaemia (CLL) | |
Michał K. Zarobkiewicz1  Agnieszka A. Bojarska-Junak1  | |
[1] Department of Clinical Immunology, Medical University of Lublin, 20-093 Lublin, Poland; | |
关键词: γδ T; Vδ1; Vδ2; Vδ3; CLL; chronic lymphocytic leukaemia; | |
DOI : 10.3390/cells11040661 | |
来源: DOAJ |
【 摘 要 】
Chronic lymphocytic leukaemia (CLL) is the most common leukaemia among adults. It is the clonal expansion of B cells expressing CD19 and CD5. Despite significant progress in treatment, CLL is still incurable. γδ T cells comprise an important subset of the cytotoxic T cells. Although γδ T cells in CLL are dysfunctional, they still can possibly be used for immunotherapy. The current paper reviews our understanding of γδ T lymphocytes in CLL.
【 授权许可】
Unknown