The prevalence of Restless Legs Syndrome/Willis-ekbom disease (RLS/WED) in the third trimester of pregnancy: a systematic review

BMC Neurology

Nader Salari¹  Niloofar Darvishi²  Aliakbar Vaisi-Raygani²  Rostam Jalali²  Masoud Mohammadi²  Alireza Abdi²  Alireza Daneshkhah³  Fateme Darvishi⁴  Behnam Khaledi-Paveh⁵ 

[1] Department of Biostatistics, School of Health, Kermanshah University of Medical Sciences;Department of Nursing, School of Nursing and Midwifery, Kermanshah University of Medical Sciences;School of Computing, Electronics and Maths, Coventry University;School of Medicine, Kermanshah University of Medical Sciences;Sleep Disorders Research Center, Kermanshah University of Medical Sciences;

关键词: Prevalence;    Restless legs syndrome;    Pregnancy;    Systematic review;   

DOI  :  10.1186/s12883-020-01709-0

来源: DOAJ

【 摘 要 】

Abstract Background RLS is known as one of the most common movement disorders during pregnancy, which is most aggravated in the third trimester of pregnancy and can affect up to one-third of pregnant women. This study intends to determine the total prevalence of RLS in the third trimester of pregnancy through a systematic review. Methods The present study was conducted via meta-analysis method up to 2019. The papers related to the subject of interest were obtained through searching in SID, MagIran, IranDoc, Scopus, Embase, Web of Science (ISI), PubMed, Science Direct, and Google Scholar databases. Heterogeneity of the studies was examined via I2 index, and the data were analyzed in Comprehensive meta-analysis software. Results In investigating 10 papers capturing 2431 subjects within the age range of 25–39 years, the total prevalence of RLS in the third trimester of pregnancy based on meta-analysis was obtained as 22.9% (95% CI: 14.7–33.8%). Further, as the sample size increased, the RLS prevalence diminished, while with increase in years, this prevalence increased, where this difference was statistically significant (P < 0.05). Conclusion Prevalence of RLS in the third trimester of pregnancy is high, healthcare policymakers should organize educational classes to improve the life dimensions among this group of pregnant women.

【 授权许可】

Unknown