Alzheimer’s disease treatment: The share of herbal medicines

Iranian Journal of Basic Medical Sciences

Mohammad Karimian¹  Masoud Soheili²  Gholamali Hamidi²  Mahmoud Salami² 

[1] Department of Molecular and Cell Biology, Faculty of Basic Sciences, University of Mazandaran, Babolsar, Iran;Physiology Research Center, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran;

关键词: alzheimer’s disease;    crocus sativus;    ginkgo biloba;    ginseng;    lavandula angustifolia;    magnolia officinalis;    melissa officinalis;    salvia miltiorrhiza;   

DOI  :  10.22038/ijbms.2020.50536.11512

来源: DOAJ

【 摘 要 】

One of the most frequent forms of dementia in neurological disorders is Alzheimer’s disease (AD). It is a chronic neurodegenerative disease characterized by impaired learning and memory. Pathological symptoms as extracellular amyloid-beta (Aβ) plaques and intracellular accumulation of neurofibrillary tangles occur in AD. Due to the aging of the population and increased prevalence of AD, discovery of new therapeutic agents with the highest effectiveness and fewer side effect seems to be necessary. Numerous synthetic medicines such as tacrine, donepezil, galantamine, rivastigmine, memantine, glutathione, ascorbic acid, ubiquinone, ibuprofen, and ladostigil are routinely used for reduction of the symptoms and prevention of disease progression. Nowadays, herbal medicines have attracted popular attention for numerous beneficial effects with little side effects. Lavandula angustifolia, Ginkgo biloba, Melissa officinalis, Crocus sativus, Ginseng, Salvia miltiorrhiza, and Magnolia officinalis have been widely used for relief of symptoms of some neurological disorders. This paper reviews the therapeutic effects of phytomedicines with prominent effects against various factors implicated in the emergence and progression of AD.

【 授权许可】

Unknown