Korelasi Antara Kadar Laktat, Base Deficit Dan Saturasi Vena Sentral Dengan Skor Multiple Organ Dysfunction Hari Ke-3 Pada Pasien Pascabedah Dengan Hemodinamik Stabil Di Ruang Perawatan Intensif Rumah Sakit Dr. Hasan Sadikin Bandung

Jurnal Anestesi Perioperatif

Ruby Satria Nugraha¹  Tatang Bisri¹  Ike Sri Redjeki² 

[1] Departemen Anestesiologi dan Terapi IntensifFakultas Kedokteran Universitas Padjadjaran Rumah Sakit Dr. Hasan Sadikin Bandung;Departemen Anestesiologi dan Terapi Intensif Fakultas Kedokteran Universitas Padjadjaran/Rumah Sakit Dr. Hasan Sadikin Bandung;

关键词: laktat;    base deficit;    saturasi vena sentral;    hipoksia jaringan;    disfungsi organ;   

DOI  :  10.15851/jap.v1n1.154

来源: DOAJ

【 摘 要 】

there is no precise indicator to evaluate adequate global perfussion yet. On haemodynamically stable patient is possible to experience change in lactate value, base deficit, and central vein saturation, which can be used to assess tissue hypoxia. The aim of this study is to find the best parameter among those three parameters toward day-third-MOD (Multiple organ dysfunction) score on hemodinamically stable post surgery patients whose been hospitalized in ICU (Intensive care unit).This is a cross-sectional observational study. The subject of this study were 50 high-risk patients whose hospitalized in RPI, male and female between 18 – 65 years old who had been done explorative laparatomy procedures under general anesthesia. Blood lactate, arterial blood gas analysis and central vein blood gas analysis had been analysis on all subjects on admissions and on the 24th hours. On the third day, MOD score that covered neurologic, cardiovascular, respiration, renal, hematologic and liver function had been assessed. This study yielded rank Spearmen coeffisien correlation between blood lactate 1 and day-third-MOD score 0,572 (p<0,001), and base deficit 1 and day-third-MOD score was 0,811 (p<0,001). The value between central vein saturation1 and day-third-MOD score, and central vein saturation 2 and day-third-MOD score were unsignificant, with rank Spearmen coeffisien correlation were 0,328 and 0,260. Good coeffisien correlation was found between blood lactate and base deficit with MOD score on third day, whilst central vein saturation hadweak coeffisien correlation. Blood lactate level and base deficit can be used to evaluate early tissue perfusion disturbances on hemodinamically stable high risk post surgery patients.

【 授权许可】

Unknown