A Facile One-Pot Synthesis of Functionalized N-Hydroxypyrrole Mediated by Vinyl-Triphenylphosphonium Salt

Iranian Journal of Chemistry & Chemical Engineering

Marjaneh Samadi Zadeh¹  Issa Yavari²  Sakineh Asghari³ 

[1] Department of Chemistry, Islamic Azad University, Science and Research Campus, Tehran, I.R. IRAN;Department of Chemistry, Tarbiat Modares University, P.O. Box 14155-4838, Tehran, I.R. IRAN;Department of Chemistry, Tarbiat Modarres University, P.O. Box 14155-4838, Tehran, I.R. IRAN;

关键词: n-hydroxypyrroles;    intramolecular;    wittig reaction;    triphenylphosphine;    acetylenic ester;    isonitrosoacetophenone;   

DOI  :  

来源: DOAJ

【 摘 要 】

Protonation of the reactive intermediates generated in the raction between dalkyl acetylenedicarboxylates and triphenylphosphine by isonitrosoacetophenone leads to vinyltriphenylphosphonium salts, which undergo intramolecular Wittig reaction to produce dalkyl 4-phenyl-N-hydroxypyrrole-2,3-dicarboxylates in moderate yields.

【 授权许可】

Unknown