Psychological model of ART adherence behaviors in persons living with HIV/AIDS in Mexico: a structural equation analysis

Revista de Saúde Pública

关键词: HIV Long-Term Survivors Acquired, psychology;    Medication Adherence;    Immunodeficiency Syndrome, drug therapy;    Models, Psychological;    Patient Medication Knowledge;    Health Knowledge, Attitudes, Practice;   

DOI  :  10.11606/s1518-8787.2017051006926

来源: DOAJ

【 摘 要 】

ABSTRACTOBJECTIVEThe objective of this study has been to test the ability of variables of a psychological model to predict antiretroviral therapy medication adherence behavior.METHODSWe have conducted a cross-sectional study among 172 persons living with HIV/AIDS (PLWHA), who completed four self-administered assessments: 1) the Psychological Variables and Adherence Behaviors Questionnaire, 2) the Stress-Related Situation Scale to assess the variable of Personality, 3) The Zung Depression Scale, and 4) the Duke-UNC Functional Social Support Questionnaire. Structural equation modeling was used to construct a model to predict medication adherence behaviors.RESULTSOut of all the participants, 141 (82%) have been considered 100% adherent to antiretroviral therapy. Structural equation modeling has confirmed the direct effect that personality (decision-making and tolerance of frustration) has on motives to behave, or act accordingly, which was in turn directly related to medication adherence behaviors. In addition, these behaviors have had a direct and significant effect on viral load, as well as an indirect effect on CD4 cell count. The final model demonstrates the congruence between theory and data (x2/df. = 1.480, goodness of fit index = 0.97, adjusted goodness of fit index = 0.94, comparative fit index = 0.98, root mean square error of approximation = 0.05), accounting for 55.7% of the variance.CONCLUSIONSThe results of this study support our theoretical model as a conceptual framework for the prediction of medication adherence behaviors in persons living with HIV/AIDS. Implications for designing, implementing, and evaluating intervention programs based on the model are to be discussed.

【 授权许可】

Unknown