Matrix Gla-protein expression in peripheral blood mononuclear cells is related to risk factors in cardiovascular diseased patients

Türk Biyokimya Dergisi

Nikolova Miglena¹  Pasheva Milena¹  Galunska Bistra¹  Vankova Deyana¹  Kiselova-Kaneva Yoana Dimitrova¹  Nazifova-Tasinova Neshe¹  Yotov Yoto²  Atanasov Atanas² 

[1] Department of Biochemistry, Molecular Medicine and Nutrigenomics, Faculty of Pharmacy, Medical University of Varna, Varna, Bulgaria;First Department of Internal Diseases, Faculty of Medicine, Medical University of Varna, Varna, Bulgaria;

关键词: biomarkers;    cardiovascular disease;    gene expression;    matrix gla-protein;    peripheral blood mononuclear cells;    biyobelirteçler;    kardiyovasküler hastalık;    matrix gla-proteini;    gen ekspresyonu;    periferik kan mononükleer hücreleri;   

DOI  :  10.1515/tjb-2021-0167

来源: DOAJ

【 摘 要 】

Matrix Gla protein (MGP) is a calcification inhibitor that plays a role in preventing soft tissue calcification and local mineralization of the vascular wall. The present study aimed to assess the expression of MGP in Peripheral Blood Mononuclear Cells (PBMC) in adult patients with CVD pathologies and its association with the presence and severity of coronary artery calcium score (CACS) and conventional CVD risk factors.

【 授权许可】

Unknown