Erysipelothrix rhusiopathiae bacteremia without endocarditis: rapid identification from positive blood culture by MALDI-TOF mass spectrometry. A case report and literature review

Infectious Disease Reports

Carola Mauri¹  Francesco Luzzaro¹  Silvia Bracco¹  Silvia Tonolo¹  Beatrice Pini¹  Luigi Principe¹ 

[1] Microbiology and Virology Unit, A. Manzoni Hospital, Lecco;

关键词: Erysipelas;    skin and soft tissue infections;    antimicrobial treatment;    empirical therapy;   

DOI  :  10.4081/idr.2016.6368

来源: DOAJ

【 摘 要 】

Erysipelothrix rhusiopathiae is a Gram-positive bacillus that is infrequently responsible for infections in humans. Three forms have been classified: a localized cutaneous form (erysipeloid) caused by traumatic penetration of E. rhusiopathiae, a generalized cutaneous form and a septicemic form. The latter type of disease has been previously associated with a high incidence of endocarditis. Here we report a case of E. rhusiopathiae bacteremia in a 74- year-old man, probably started from an erysipeloid form, in which endocarditis did not develop. This case presents some particular and uncommon features: i) no correlation with animal source; ii) correlation between bacteremia and erysipeloid lesion; iii) absence of endocarditis. MALDI-TOF mass spectrometry allowed to obtain a rapid identification (within 4 hours from bottle positivity) of E. rhusiopathiae. Together with direct antimicrobial susceptibility testing, this approach could improve the rate of appropriate therapy for bloodstream infections due to this fastidious pathogen.

【 授权许可】

Unknown