Clinical Therapy of Metastatic Spinal Tumors

Frontiers in Surgery

Yuanyi Wang¹  Yadong Liu¹  Feng Xu¹  Changfeng Fu¹  Wenjie Wei²  Jie Li³ 

[1] Department of Spine Surgery, The First Hospital of Jilin University, Changchun, China;Key Laboratory of Pathobiology, Ministry of Education, School of Basic Medical Sciences, Jilin University, Changchun, China;Key Laboratory of Polymer Ecomaterials, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun, China;

关键词: metastatic spinal tumor;    surgical management;    minimally invasive therapy;    radiation therapy;    systemic therapy;   

DOI  :  10.3389/fsurg.2021.626873

来源: DOAJ

【 摘 要 】

Metastatic spinal tumors (MST) have high rates of morbidity and mortality. MST can destroy the vertebral body or compress the nerve roots, resulting in an increased risk of pathological fractures and intractable pain. Here, we elaborately reviewed the currently available therapeutic options for MST according to the following four aspects: surgical management, minimally invasive therapy (MIT), radiation therapy, and systemic therapy. In particular, these aspects were classified and introduced to show their developmental process, clinical effects, advantages, and current limitations. Furthermore, with the improvement of treatment concepts and techniques, we discovered the prevalent trend toward the use of radiation therapy and MIT in clinic therapies. Finally, the future directions of these treatment options were discussed. We hoped that along with future advances and study will lead to the improvement of living standard and present status of treatment in patients with MST.

【 授权许可】

Unknown