Pediatric stiff-person syndrome with renal failure

Journal of Neurosciences in Rural Practice

M. Veerendra Kumar¹  P. Savida¹ 

[1] Department of Pediatrics, Government Medical College, Kottayam, Kerala, India;

关键词: glutamic acid decarboxylase;    myoclonus;    rituximab;    stiff-person syndrome;   

DOI  :  10.4103/0976-3147.165352

来源: DOAJ

【 摘 要 】

Stiff-person syndrome (SPS) is an autoimmune neuronitis with progressive myoclonus and stiffness. It is a rare but treatable disorder with few case reports in children. SPS is due to autoantibodies against the enzyme glutamic acid decarboxylase which is present in neuronal and nonneuronal tissues. This is the case report of an 8-year-old boy with clinical and investigational features suggestive of SPS with associated myoglobin-induced renal failure, who completely recovered with treatment.

【 授权许可】

Unknown