Impact of different image guidance schedules in head and neck irradiation: A retrospective analysis

Precision Radiation Oncology

Vikas Digambar Kothavade¹  Jatin Vinod Bhatia¹  Vinoth Kumar Ramachandran¹ 

[1] Department of Radiation Oncology Jupiter Hospital Pune Maharashtra India;

关键词: head and neck irradiation;    image guidance frequency;    image‐guided radiation therapy;   

DOI  :  10.1002/pro6.1109

来源: DOAJ

【 摘 要 】

Abstract Objective Is daily image‐guided radiation therapy justified for all patients? Here, we attempt to address this issue and present data obtained from various frequencies. Methods All consecutive head and neck cancer patients receiving radiation with curative intent and daily image‐guided radiation therapy using kV cone beam computed tomography scans were eligible. Displacements in the medial–lateral, superior–inferior (SI), and anterior–posterior directions were documented daily. The retrospectively simulated scenarios with reducing frequency were 50%, 30%, 20%, and 10%. The mean displacements, systematic errors, random errors, and planning target volume margins were calculated. Results A total of 831 cone beam computed tomography scans of 31 patients were analyzed, showing normally distributed mean displacements in the medial–lateral, SI, and anterior–posterior direction, except in SI for daily format. The mean displacements in the three directions was <0.1 cm, reflected in the systematic errors (<0.2 cm). In the SI direction, the random errors for daily format were 0.7 cm and 0.2 cm for simulated scenarios; these differences were demonstrated in planning target volume margin calculation, 1 cm in the SI direction based on daily data, and 0.5 cm based on simulated scenarios. The margin estimation was similar in the other directions for all formats. Conclusion The errors were similar across all scenarios, inconclusive of superiority for any schedule; however, a higher random error was observed with daily format in the SI direction. Our findings further validate the need for more data to determine the optimum image‐guided radiation therapy frequency.

【 授权许可】

Unknown