Seroprevalence canine survey for selected vector-borne pathogens and its relationship with poverty in metropolitan Pereira, Colombia, 2020

Parasite Epidemiology and Control

María Angelica Reina-Mora¹  Álvaro A. Faccini-Martínez²  Alfonso J. Rodríguez-Morales³  Ingrid Lorena Jaramillo-Delgado⁴  Luz Victoria González-Colonia⁴  Jean Carlos Salazar⁴  Erwin J. Gutiérrez-Grajales⁴  Daniela Osorio-Navia⁴  Lorenzo Valencia-Mejía⁴  Eduardo Ramírez-Vallejo⁴  Erika Vanessa Jiménez-Posada⁴  Fausto Muñoz-Lara⁴  J. Paola Martínez-Arboleda⁵  Alberto Paniz-Mondolfi⁶  Adrián E. Trejos-Mendoza⁷  Samuel Pecho-Silva⁸  Jaime A. Cardona-Ospina⁹  Manuel Sierra⁹  Mariana Chacón-Peña⁹  Juan Camilo Álvarez⁹  Luisa F. Marín-Arboleda⁹  D. Katterine Bonilla-Aldana⁹  Lysien I. Zambrano⁹  Andrés Diaz⁹  Soffia Pérez-Vargas⁹ 

[1] Committee of Tropical Medicine, Zoonoses and Travel Medicine, Asociación Colombiana de Infectología, Bogotá, Colombia;Grupo de Investigación Biomedicina, Faculty of Medicine, Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia;Grupo de Investigación en Infecciones Emergentes y Medicina Tropical, Instituto para la Investigación en Ciencias Biomédicas, SCI-HELP, Pereira, Risaralda, Colombia;Institución Universitaria Visión de las Américas, Pereira, Risaralda, Colombia;Red Colombiana de Enfermedades Transmitidas por Garrapatas en Pequeños Animales (RECEPA) – Colombian Network of Tick-Borne Diseases in Small Animals (RECEPA), Pereira, Risaralda, Colombia;Institución Universitaria Visión de las Américas, Pereira, Risaralda, Colombia;Red Colombiana de Enfermedades Transmitidas por Garrapatas en Pequeños Animales (RECEPA) – Colombian Network of Tick-Borne Diseases in Small Animals (RECEPA), Pereira, Risaralda, Colombia;San Lucas Centro Veterinario y Diagnóstico, Pereira, Risaralda, Colombia;Semillero de Investigación en Zoonosis (SIZOO), Fundación Universitaria Autónoma de las Américas, Pereira, Risaralda, Colombia;

关键词: Anaplasma phagocytophilum;    Anaplasma platys;    Ehrlichia canis;    Ehrlichia ewingii;    Dirofilaria immitis;    Tick-borne diseases;   

DOI  :  

来源: DOAJ

【 摘 要 】

Background: Tick-borne diseases (TBD) and dirofilariosis are currently not under surveillance in most Latin American countries. In addition, there is a significant lack of studies describing the current situation in most endemic areas, including Colombia. Therefore, seroprevalence studies are crucial for understanding the epidemiology of these vector-borne diseases. Methods: A serosurvey for TBD and dirofilariosis among 100 dogs was carried out in the municipality of Pereira, located in the Coffee-Triangle region, Colombia. Samples were tested using a rapid assay test system (SNAP® 4Dx®); based on an enzyme immunoassay technique‚ screening for antibodies to Anaplasma phagocytophilum/platys (sensitivity 99.1%)‚ Borrelia burgdorferi s.l. (98.8%), and Ehrlichia canis/ewingii (96.2%) by using specific antigens and checking for Dirofilaria immitis antigen based on specific antibodies (99.2%). Bivariate analyses were performed on Stata®14, significant p < 0.05. Findings: Global seroprevalence to the selected vector-borne pathogens was 74% (95%CI 65–83%). The highest seroprevalence was found for E. canis/ewingii (74%), followed by A. phagocytophilum/platys (16%). Seropositivity for Borrelia spp. and Dirofilaria spp. was 0%. All Anaplasma spp. seropositive dogs showed co-detection of Ehrlichia spp. (16%). Seroprevalence was significantly higher among dogs from families of lower socioeconomic status/level (I, 86%), followed by level II (74%), and III (36%) (p = 0.001). All dogs exhibiting anorexia (12%) were invariably seropositive (100%) (p = 0.029). Seroprevalence was higher among those showing mucocutaneous paleness (95%) compared to those without paleness (68%) (p = 0.013) (OR = 9.3; 95%CI 1.18–72.9). There was high variability in seroprevalence through the studied areas, ranging from 0% (La Libertad Park) up to Combia, Cesar Nader, Las Brisas and Saturno localities (100%) (p = 0.033). Interpretation: Given the high seroprevalence obtained in an area with documented ticks, there is a potential risk of zoonotic transmission to humans. Further seroprevalence studies in humans are needed to assess the prevalence of infections. Poverty is highly associated with these tick-borne pathogens in Pereira, as shown in the present study.

【 授权许可】

Unknown