Cryoglobulin studies in systemic lupus erythematosus.

Journal of Postgraduate Medicine

关键词: Adolescent;    Adult;    Aged;    Cryoglobulins;    analysis;    immunology;    Human;    Immunoglobulin A;    immunology;    Immunoglobulin G;    immunology;    Immunoglobulin M;    immunology;    Lupus Erythematosus;    Systemic;    etiology;    immunology;    Middle Age;   

DOI  :  

来源: DOAJ

【 摘 要 】

Twenty-two patients with systemic lupus erythematosus (SLE) were investigated to study the incidence and immunochemical nature of circulating immune complexes. In 68.18% of patients, the immune complexes were detected as cryoglobulins. A significantly high value of serum IgG and IgA (1980.64 +/- 1031.53 and 283.81 +/- 131.02 mg% respectively) were observed in these patients compared to those in normal (1097.04 +/- 298.10 and 200.93 +/- 89.96 mg% respectively). The patients also had significantly low levels of serum complement fraction C3 (61.35 +/- 22.64 mg%). Correlation of these parameters could help in understanding of the role of immunochemical factors in the pathogenesis of the disease.

【 授权许可】

Unknown