Antioxidant Properties of Ester Derivatives of Cinnamic and Hydroxycinnamic Acids in Nigella sativa and Extra-Virgin Olive Oils-Based Emulsions

Antioxidants

Diego Romano Perinelli¹  Marco Cespi¹  Giulia Bonacucina¹  Giovanni Filippo Palmieri¹  Elisabetta Torregiani¹  Rosita Gabbianelli² 

[1] Chemistry Interdisciplinary Project (CHIP), School of Pharmacy, Via Madonna delle Carceri, University of Camerino, 62032 Camerino, Italy;Unit of Molecular Biology and Nutrigenomics, School of Pharmacy, University of Camerino, 62032 Camerino, Italy;

关键词: polyphenols;    ferulic acid;    cinnamic acid;    Nigella sativa oils;    extra-virgin olive oil (EVO);   

DOI  :  10.3390/antiox11020194

来源: DOAJ

【 摘 要 】

New hydrophobic derivatives of cinnamic and hydroxycinnamic (ferulic and cumaric) acids obtained by chemical esterification of the carboxylic group with C10 linear alcohol were studied to evaluate their antioxidant capacity toward the superoxide anion and hydrogen peroxide in physiological buffer and in extra-virgin olive oil (EVO) or Nigella sativa oils. Results showed that cumaric and ferulic acids have higher antioxidants activity against superoxide anion and hydrogen peroxide than the other compounds. Cumaric acid and its C10-ester derivative were selected to be incorporated into EVO or Nigella sativa oil-based emulsions. The prepared emulsions had a comparable particle size distribution (in the range of 3–4 µm) and physical stability at least up to three months. Nigella sativa oil-based emulsions loaded with cumaric acid or its C10-ester showed a higher capacity to scavenger superoxide anion and hydrogen peroxide than EVO oil-based emulsions. In conclusion, cumaric acid or its C10-ester could promote the antioxidant properties of Nigella sativa oil when formulated as emulsions.

【 授权许可】

Unknown