Journal of Lipid Research | |
High prevalence of low HDL cholesterol concentrations and mixed hyperlipidemia in a Mexican nationwide survey | |
Gustavo Olaiz1  Francisco J. Gómez Pérez2  Juan Manuel Ríos Torres2  Juan A. Rull2  Rosalba Rojas2  Victoria Valles3  Jaime Sepulveda3  Aurora Franco3  Carlos A. Aguilar-Salinas4  | |
[1] Departamento de Endocrinología y Metabolismo de Lípidos, del Instituto Nacional de Ciencias Médicas y Nutrición, Vasco de Quiroga 15, Mexico City 14000, Mexico;Departamento de Endocrinología y Metabolismo de Lípidos, del Instituto Nacional de Ciencias Médicas y Nutrición, Vasco de Quiroga 15, Mexico City 14000, Mexico;Instituto Nacional de Salud Publica, Cuernavaca, Morelos, Mexico;To whom correspondence should be addressed.; | |
关键词: diabetes; obesity; hypertension; cholesterol; Mexico; insulin resistance; | |
DOI : | |
来源: DOAJ |
【 摘 要 】
The prevalence of lipid abnormalities revealed in a survey done in 417 Mexican cities is described. Information was obtained on 15,607 subjects, aged 20 to 69 years. In this report, only samples obtained after a 9- to 12-h fast were included (2,256 cases: 953 men and 1,303 women). The population is representative of Mexican urban adults. Mean lipid concentrations were: cholesterol, 4.80 mmol/l; triglycerides, 2.39 mmol/l; HDL cholesterol, 1.00 mmol/l; and LDL cholesterol, 3.06 mmol/l. The most prevalent abnormality was HDL cholesterol below 0.9 mmol/l (46.2% for men and 28.7% for women). Hypertriglyceridemia (>2.26 mmol/l) was the second most prevalent abnormality (24.3%). Severe hypertriglyceridemia (>11.2 mmol/l) was observed in 0.42% of the population. Increased LDL cholesterol (≥4.21 mmol/l) was observed in 11.2% of the sample. Half of the hypertriglyceridemic subjects had a mixed dyslipidemia or low HDL cholesterol. More than 50% of the low HDL cholesterol cases were not related to hypertriglyceridemia. Insulin resistance was found in 59% of them. In conclusion, the prevalence of hypoalphalipoproteinemia and other forms of dyslipidemia in Mexican adults is very high and it is among the highest previously reported worldwide. —Aguilar-Salinas, C. A., G. Olaiz, V. Valles, J. M. Ríos Torres, F. J. Gómez Pérez, J. A. Rull, R. Rojas, A. Franco, and J. Sepulveda. High prevalence of low HDL cholesterol concentrations and mixed hyperlipidemia in a Mexican nationwide survey.
【 授权许可】
Unknown