A Rare Case of Primary Tubular Adenocarcinoma of the Thymus, Enteric Immunophenotype: A Case Study and Review of the Literature

Journal of Pathology and Translational Medicine

Jin-Haeng Chung¹  Sang Byoung Bae²  Hyun Ju Lee³  Hyundeuk Cho³  Ji-Hye Lee³  Si-Hyong Jang³  Mee-Hye Oh³ 

[1] Department of Pathology and Respiratory Center, Seoul National University Bundang Hospital, Seongnam, Korea;Division of Hematology and Oncology, Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Korea;;

关键词: Thymus gland;    Adenocarcinoma;    Keratin-20;    Caudal type homeobox 2;   

DOI  :  10.4132/jptm.2015.04.16

来源: DOAJ

【 摘 要 】

Thymic carcinomas are uncommon malignant tumors, and thymic adenocarcinomas are extremely rare. Here, we describe a case of primary thymic adenocarcinoma in a 59-year-old woman. Histological examination of the tumor revealed tubular morphology with expression of cytokeratin 20 and caudal-type homeobox 2 according to immunohistochemistry, suggesting enteric features. Extensive clinical and radiological studies excluded the possibility of an extrathymic primary tumor. A review of the literature revealed only two global cases of primary tubular adenocarcinomas of the thymus with enteric immunophenotype.

【 授权许可】

Unknown