Changes in Lipid Profile, Body Weight Variables and Cardiovascular Risk in Obese Patients Undergoing One-Anastomosis Gastric Bypass

International Journal of Environmental Research and Public Health

María-José Castro¹  Jose-Maria Jiménez¹  Miguel-Angel Carbajo¹  Jaime Rúiz-Tovar¹  María-José Cao²  Sara García²  María López² 

[1] Center of Excellence for the Study and Treatment of Diabetes and Obesity, 47004 Valladolid, Spain;Nursing Faculty, University of Valladolid, 47005 Valladolid, Spain;

关键词: morbid obesity;    lipid profile;    weight loss;    one-anastomosis gastric bypass;    cardiovascular risk;   

DOI  :  10.3390/ijerph17165858

来源: DOAJ

【 摘 要 】

Morbid obesity has a direct impact on the development of cardiovascular disease. One-anastomosis gastric bypass (OAGB) is an effective surgical technique for the control of body weight and the reduction of cardiovascular risk. This work examines the change in weight loss, lipid profile and cardiovascular risk in 100 patients (71 women, 29 men), mean age 42.61 ± 11.33 years at 3, 6, 9, 12, 18 and 24 months after OAGB. At 24 months post-surgery, mean body weight was significantly reduced compared to pre-operative values (116.75 ± 22.19 kg vs. 69.66 ± 13.07 kg), as were mean total cholesterol (201.86 ± 44.60 mg/dL vs. 172.99 ± 32.26 mg/dL), LDL (Low-Density Lipoprotein) cholesterol (126.90 ± 39.81 mg/dL vs. 96.28 ± 26.99 mg/dL), triglycerides (138.05 ± 78.45 mg/dL vs. 76.04 ± 30.34 mg/dL) and cardiovascular risk (total cholesterol/HDL (High-Density Lipoprotein) cholesterol: 4.32 ± 1.24 vs. 2.93 ± 0.71), while the mean HDL cholesterol concentration was significantly higher (49.09 ± 14.16 mg/dL vs. 61.98 ± 14.86 mg/dL) (all p < 0.001). In conclusion, OAGB surgery led to significant reductions in body weight, a significant improvement in the lipid profile, and a reduction in cardiovascular risk.

【 授权许可】

Unknown