Inflammation and dry eye disease—where are we?

International Journal of Ophthalmology

Nikhil Gokhale¹  Rishi Mohan²  Himanshu Matalia³  Paras Mehta⁴  Srinivas K Rao⁵ 

[1] Gokhale Eye Hospital, Mumbai, Maharashtra 400028, India;MM Eyetech Institute of Ophthalmology, New Delhi 110024, India;Narayana Nethralaya, Electronic City, Bangalore 560001, Karnataka, India;Sameep Eye Hospital and Corneal Center, Vadodara 390006, Gujarat, India;Srinivas K Rao. Darshan Eye Care & Surgical Centre, Chennai, Tamil Nadu 600040, India. [e-mail];

关键词: dry eye disease;    inflammation;    meibomian gland dysfunction;    vicious cycle;    ocular surface disease;   

DOI  :  10.18240/ijo.2022.05.20

来源: DOAJ

【 摘 要 】

The presence of inflammation in dry eye disease (DED) results in increased patient symptomatology, ocular surface damage and worsening tear dysfunction. It also affects the health of meibomian glands and their secretions which further aggravates ocular surface disease. This article reviews current knowledge regarding ocular surface inflammation in DED and explores the relationships between the vicious cycles of DED, inflammation and meibomian gland dysfunction (MGD). The clinical evaluation of eyes with such changes, markers that identify the presence of inflammation on the ocular surface and current treatment options are discussed.

【 授权许可】

Unknown