Silver Doped Magnesium Ferrite Nanoparticles: Physico-Chemical Characterization and Antibacterial Activity

Materials

Cinzia Calvio¹  Erlinda Rama¹  Erika Fantozzi²  Marcella Bini²  Benedetta Albini³  Pietro Galinetto³ 

[1] Department of Biology and Biotechnology “L. Spallanzani”, University of Pavia, via Ferrata 9, 27100 Pavia, Italy;Department of Chemistry, University of Pavia, Viale Taramelli 16, 27100 Pavia, Italy;Department of Physics and CNISM, University of Pavia, via Bassi 6, 27100 Pavia, Italy;

关键词: MgFe₂O₄;    X-ray powder diffraction;    micro-Raman;    Ag doping;    antibacterial activity;   

DOI  :  10.3390/ma14112859

来源: DOAJ

【 摘 要 】

Spinel phases, with unique and outstanding physical properties, are attracting a great deal of interest in many fields. In particular, MgFe₂O₄, a partially inverted spinel phase, could find applications in medicine thanks to the remarkable antibacterial properties attributed to the generation of reactive oxygen species. In this paper, undoped and Ag-doped MgFe_2-xAg_xO₄ (x = 0.1 and 0.3) nanoparticles were prepared using microwave-assisted combustion and sol–gel methods. X-ray powder diffraction, with Rietveld structural refinements combined with micro-Raman spectroscopy, allowed to determine sample purity and the inversion degree of the spinel, passing from about 0.4 to 0.7 when Ag was introduced as dopant. The results are discussed in view of the antibacterial activity towards Escherichia coli and Staphylococcus aureus, representative strains of Gram-negative and Gram-positive bacteria. The sol–gel particles were more efficient towards the chosen bacteria, possibly thanks to the nanometric sizes of metallic silver, which were well distributed in the powders and in the spinel phase, with respect to microwave ones, that, however, acquired antibacterial activity after thermal treatment, probably due to the nucleation of hematite, itself displaying well-known antibacterial properties and which could synergistically act with silver and spinel.

【 授权许可】

Unknown