Coxiella burnetii vascular graft infection

IDCases

Fernando Casado Castillo¹  Takaaki Kobayashi²  Loreen Herwaldt³  Jason H. Barker³ 

[1] Division of Infectious Diseases, Department of Internal Medicine, University of Iowa Hospitals and Clinics, United States;Corresponding authors.;Division of Infectious Diseases, Department of Internal Medicine, University of Iowa Hospitals and Clinics, United States;

关键词: Coxiella burnetii;    Vascular graft infection;   

DOI  :  

来源: DOAJ

【 摘 要 】

Q fever, a zoonotic infection caused by Coxiella burnetii, can present with a wide spectrum of clinical manifestations. The organism is typically transmitted from sheep, goats, or cattle to humans via contaminated aerosols. On average, 1–5% of patients with acute Q fever will develop chronic infection months to decades after their primary infections. We report a case of a chronic vascular graft infection due to Coxiella burnetii in a 61-year-old man without direct exposure to animals who presented with recurrent fever. Indium-111-labeled white blood cell scan with single-emission positron computed tomography demonstrated findings suggesting a graft infection. C. burnetii phase I and phase II IgG antibody titers were > 1:32,768 and polymerase chain reaction performed on the explanted graft was positive for C. burnetii. Q fever should be considered in the differential diagnosis of vascular infections in patients who have a pre-existing lesion such as an aneurysm, or vascular prosthesis even in the absence of a history of direct animal exposure.

【 授权许可】

Unknown