Characterization of a Functional Hydrogel Layer on a Silicon-Based Grating Waveguide for a Biochemical Sensor

Sensors

Jongseong Kim¹  Yoo-Seung Hong²  Hyuk-Kee Sung² 

[1] Department of Neurology, Molecular Imaging and Neurovascular Research (MINER) Laboratory, Dongguk University Ilsan Hospital, Goyang 10326, Korea;School of Electronic and Electric Engineering, Hongik University, Seoul 121-791, Korea;

关键词: waveguides;    diffraction gratings;    biological sensing and sensors;    optical sensing and sensors;   

DOI  :  10.3390/s16060914

来源: DOAJ

【 摘 要 】

We numerically demonstrated the characteristics of a functional hydrogel layer on a silicon-based grating waveguide for a simple, cost-effective refractive index (RI) biochemical sensor. The RI of the functional hydrogel layer changes when a specific biochemical interaction occurs between the hydrogel-linked receptors and injected ligand molecules. The transmission spectral profile of the grating waveguide shifts depends on the amount of RI change caused by the functional layer. Our characterization includes the effective RI change caused by the thickness, functional volume ratio, and functional strength of the hydrogel layer. The results confirm the feasibility of, and set design rules for, hydrogel-assisted silicon-based grating waveguides.

【 授权许可】

Unknown