Graphene-based nanomaterials for cancer therapy and anti-infections

Bioactive Materials

Juan Li¹  Xiaobin Li²  Jinping Shi³  Zhaotan Jiang⁴  Yan Wang⁴  Can Yang Zhang⁴ 

[1] Institute of Biopharmaceutical and Health Engineering, Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China;Advanced Research Institute for Multidisciplinary Science, Beijing Institute of Technology, Beijing, 100081, China;Institute of Biopharmaceutical and Health Engineering, Shenzhen International Graduate School, Tsinghua University, Shenzhen, 518055, China;School of Physics, Beijing Institute of Technology, Beijing, 100081, China;

关键词: Graphene;    Phototherapy;    Cancer therapy;    Anti-infection;    2D materials;   

DOI  :  

来源: DOAJ

【 摘 要 】

Graphene-based nanomaterials (GBNMs) has been thoroughly investigated and extensively used in many biomedical fields, especially cancer therapy and bacteria-induced infectious diseases treatment, which have attracted more and more attentions due to the improved therapeutic efficacy and reduced reverse effect. GBNMs, as classic two-dimensional (2D) nanomaterials, have unique structure and excellent physicochemical properties, exhibiting tremendous potential in cancer therapy and bacteria-induced infectious diseases treatment. In this review, we first introduced the recent advances in development of GBNMs and GBNMs-based treatment strategies for cancer, including photothermal therapy (PTT), photodynamic therapy (PDT) and multiple combination therapies. Then, we surveyed the research progress of applications of GBNMs in anti-infection such as antimicrobial resistance, wound healing and removal of biofilm. The mechanism of GBNMs was also expounded. Finally, we concluded and discussed the advantages, challenges/limitations and perspective about the development of GBNMs and GBNMs-based therapies. Collectively, we think that GBNMs could be potential in clinic to promote the improvement of cancer therapy and infections treatment.

【 授权许可】

Unknown