Novel approaches to tuberculosis vaccine development

International Journal of Infectious Diseases

C. Fordham von Reyn¹  January Weiner²  Stefan H.E. Kaufmann² 

[1] Infectious Disease and International Health, Geisel School of Medicine, Hanover, New Hampshire, USA;Max Planck Institute for Infection Biology, Department of Immunology, Charitéplatz 1, 10117 Berlin, Germany;

关键词: Preventive vaccine;    Therapeutic vaccine;    Pre-exposure vaccine;    Post-exposure vaccine;    Subunit vaccine;    Whole-cell vaccine;   

DOI  :  10.1016/j.ijid.2016.10.018

来源: DOAJ

【 摘 要 】

Tuberculosis (TB) remains the deadliest infectious disease. The widely used bacille Calmette–Guérin (BCG) vaccine offers only limited protection against TB. New vaccine candidates for TB include subunit vaccines and inactivated whole-cell vaccines, as well as live mycobacterial vaccines. Current developments in TB vaccines are summarized in this review.

【 授权许可】

Unknown