One Step Preparation of Peptide-Coated Gold Nanoparticles with Tunable Size

Materials

Yongmei Jia¹  Guohua Zhou¹  Peilian Liu¹  Xin Guo¹  Xiaoning Yan¹  Zhiguo Li¹ 

[1] Key Laboratory of Clean Energy Materials Chemistry of Guangdong Higher Education Institutes, School of Chemistry and Chemical Engineering, Lingnan Normal University, Cunjin Road, Zhanjiang 524048, China;

关键词: CALNN;    peptide;    gold nanoparticle;    self-assembling;    size;    tyrosine;    trypsin;   

DOI  :  10.3390/ma12132107

来源: DOAJ

【 摘 要 】

Gold nanoparticles (AuNPs) made from self-assembling peptides have been used in many research fields and attracted a great deal of attention due to their high stability, biocompatibility and functionality. However, existing preparation methods for peptide-coated AuNPs are post-synthesis processes, which are complicated and time consuming. Therefore, a one-step preparation method for peptide-coated AuNPs is proposed here. The AuNPs obtained by this method exhibit good stability. Importantly, peptide-coated AuNPs with precise different sizes can be prepared by this method through pH control of reducing reagent tyrosine in range of 10.0~12.7. Thus, the one-step preparation method proposed here provides a significant tool for the research in different fields concerning NP size, stability and biocompatibility.

【 授权许可】

Unknown