Rare Autism-Associated Variants Implicate Syntaxin 1 (STX1 R26Q) Phosphorylation and the Dopamine Transporter (hDAT R51W) in Dopamine Neurotransmission and Behaviors

EBioMedicine

Kevin Erreger¹  Etienne Cartier¹  Aurelio Galli¹  Heinrich J.G. Matthies¹  Christine Saunders²  Andrea N. Belovich²  Aparna Shekar²  Jeremy Veenstra-Vanderweele³  Paula G. Ulery-Reynolds⁴  Ulrik Gether⁵  Thorvald F. Andreassen⁵  Peter J. Hamilton⁶  Nicholas G. Campbell⁶  James S. Sutcliffe⁶ 

[1] Department of Molecular Physiology & Biophysics, Vanderbilt University School of Medicine, Nashville, TN 37232-8548, United States;Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, TN 37232-8548, United States;Department of Psychiatry and New York State Psychiatric Institute, Columbia University, New York, NY 10032, United States;Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX 75390-8813, United States.;Molecular Neuropharmacology and Genetics Laboratory, Department of Neuroscience and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2200 Copenhagen, Denmark;Vanderbilt Brain Institute, Vanderbilt University School of Medicine, Nashville, TN 37232-8548, United States;

关键词: Autism spectrum disorder;    Dopamine;    Transporter;    Drosophila;    Syntaxin 1;    Casein kinase 2;   

DOI  :  10.1016/j.ebiom.2015.01.007

来源: DOAJ

【 授权许可】

Unknown