VITAMIN D PROVISION FOR BABIES

Rossijskij Vestnik Perinatologii i Pediatrii

G. S. Anisimov¹  E. A. Evseeva²  I. N. Zakharova²  V. A. Kuryaninova³  A. N. Kasyanova³  D. V. Bobryshev³  L. Ya. Klimov³  S. V. Dolbnya³  I. D. Maikova⁴ 

[1] North-Caucasus Federal University, Ministry of Education and Science of the Russian Federation, Stavropol;Russian Medical Academy of Postgraduate Education, Ministry of Health of Russia, Moscow;Stavropol State Medical University, Ministry of Health of Russia, Stavropol;Z.A. Bashlyaeva City Children’s Clinical Hospital, Moscow, Russia;

关键词: babies;    vitamin d;    vitamin d status;    calcidiol;    25(oh)d;    prevention of hypovitaminosis d;   

DOI  :  10.21508/1027-4065-2016-61-6-68-76

来源: DOAJ

【 摘 要 】

The study estimated vitamin D provision for babies in relation to the type of their feeding and the efficiency of drug donations of cholecalciferol preparations. A total of 132 babies aged 1 to 12 months were examined. Vitamin D deficiency was shown to occur in more than half (58.3%) of the babies at the solar minimum. If hypovitaminosis D was not prevented using drugs, the serum 25(OH)D level in the breastfed babies was 8.7 (6.3-14.8) ng/ml, which was significantly lower than that in formula-fed ones [24.55 (19.0-32.0) ng/ml] (p=0.00002). Cholecalciferol taken by the infants in a preventive dose of 500-1500 IU/day substantially increased their provision with vitamin D from 19.8 (10.4–26.3) to 32.7 (24.5-45.7) ng/ml (p=0.0000007), regardless of the feeding pattern. The serum calcidiol level is closely correlated with the dose of cholecalciferol (r=0.57; p<0.0001), the use of preparations containing vitamin D in a dose of 1000-1500 IU/day significantly improves the level of its provision throughout the first year of life, without increasing the risk of overdose.

【 授权许可】

Unknown