MiRNA-QC-and-Diagnosis: An R package for diagnosis based on MiRNA expression

SoftwareX

Simone Detassis¹  Michela Alessandra Denti¹  Michele Castelluzzo²  Alessio Perinelli²  Leonardo Ricci² 

[1] Department of Cellular, Computational and Integrative Biology (CIBIO), University of Trento, 38123 Trento, Italy;Department of Physics, University of Trento, 38123 Trento, Italy;

关键词: MiRNA;    Biomarkers;    Diagnosis;    Statistical analysis;   

DOI  :  

来源: DOAJ

【 摘 要 】

The possibility of using microRNA (miRNA) levels as diagnostic and prognostic tools to detect different pathologies requires the implementation of reliable classifiers, whose training and use call for quality control of data corresponding to miRNA expression. In this work we present the MiRNA-QC-and-Diagnosis package. The package provides a set of functions for the R environment that implement the required quality control steps and thereupon allow to train, use and optimize a Bayesian classifier for diagnosis based on the measured miRNA expressions. The package thus makes up a complete and dedicated analytical toolbox for miRNA-based diagnosis.

【 授权许可】

Unknown