LncRNA PVT1 promotes proliferation and invasion through enhancing Smad3 expression by sponging miR-140-5p in cervical cancer

Radiology and Oncology

Chang Shuai¹  Chen Zhao²  Chen Chun-Yan³  Chang Qing-Qing³ 

[1] Changsha Medical University, Changsha, Hunan Province, China;Department of Hematology, Hunan Provincial People’s Hospital, Changsha, Hunan Province, China;Department of Obstetrics and Gynecology, Hunan Provincial People’s Hospital, Changsha, Hunan Province, China;

关键词: cervical cancer;    lncrna pvt1;    mir-140-5p;    smad3;   

DOI  :  10.2478/raon-2019-0048

来源: DOAJ

【 摘 要 】

Cervical cancer is one of the most frequent malignancies among females worldwide. Increasing evidence have indicated the participation of long noncoding RNAs (lncRNAs) in the progression and metastasis of cervical cancer. Our present study was conducted to explore the effects of lncRNA plasmacytoma variant translocation 1 (PVT1) on the progression of cervical cancer and the underlying mechanisms.

【 授权许可】

Unknown