Ultrasonic characteristics of immune bodies in children with infectious mononucleosis

Žurnal Infektologii

L. A. Perminova¹  I. A. Stepanyan²  S. A. Perepelitsa²  E. V. Zakhar² 

[1] Research Institute of General Reanimatology named after V.A. Negovsky of Federal Research and Clinical Center of Intensive Care Medicine and Rehabilitology;Baltic Federal University named after Imannuel Kant;

关键词: infectious mononucleosis;    diagnostics;    splenomegaly;    ultrasound;   

DOI  :  10.22625/2072-6732-2020-12-5-78-84

来源: DOAJ

【 摘 要 】

Diagnostic morphometric criteria for splenomegaly in children with infectious mononucleosis are established using ultrasound. The study included 29 children with infectious mononucleosis. The average age is 11.7 ± 3.5 years. A morphometric measurement of the length, width and thickness of the spleen, elastometry (EM), and lymph nodes were evaluated. The spleen mass was determined by method of O.V. Vozgoment, coefficients: the ratio of spleen mass to body mass (KMS, Km), body length (KI), body surface area (Ks). The average CCM value was 6,47 ± 2,8, the absolute value of the indicator varied from 1,9 to 14,2. According to the CCM, patients are divided into 3 groups: group A – 6 (20,7%), group B – 11 (38%), group C – 12 (41,3%). The average mass of the spleen was 332,5 ± 119.6 g, the CMS – from 7,7 to 14,2, the average value of the indicator – 8,6 ± 1,9. In group B the mass of the spleen, compared with group C is 1,2 times less. In group C the spleen mass is statistically significantly greater compared with groups A and B. In group C, spleen rigidity was increased in 42,9% of cases. The average EM value is 15,8 ± 4,8 kPa. A negative correlation between the average strength between EM and age (r = – 0,65, p = 0,01) was revealed. A direct relationship was found between the mass of the spleen and the CMS, and lymphadenopathy of various localization, often periportal lymph nodes.

【 授权许可】

Unknown