MR-Guided Radiotherapy for Rectal Cancer: Current Perspective on Organ Preservation

Frontiers in Oncology

Michael Bassetti¹  Martijn Intven³  Cihan Gani⁴  Luca Boldrini⁵  Vincenzo Valentini⁵ 

[1] Department of Human Oncology, University of Wisconsin-Madison, Madison, WI, United States;Department of Radiation Oncology, Eberhard Karls Universität Tübingen, Tübingen, Germany;Department of Radiation Oncology, University Medical Center Utrecht, Utrecht, Netherlands;German Cancer Consortium (DKTK), Partner Site, Tübingen, Germany;Istituto di Radiologia, Università Cattolica del Sacro Cuore, Roma, Italy;Unità Operativa Complessa Radioterapia Oncologica, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Fondazione Policlinico Universitario “A. Gemelli” IRCCS, Roma, Italy;

关键词: radiotherapy;    rectal cancer;    MRI;    MR-linac;    dose escalation;   

DOI  :  10.3389/fonc.2021.619852

来源: DOAJ

【 摘 要 】

Online MRI-guided radiotherapy (MRgRT) is one of the most recent technological advances in radiotherapy. MRgRT permits the visualization of tumorous and healthy tissue while the patient is on the treatment table and online daily plan adaptations following the observed anatomical changes. In the context of rectal cancer, online MRgRT is a very promising modality due to the pronounced geographical variability of tumor tissues and the surrounding healthy tissues. This current paper will discuss the possible applications of online MRgRT, in particular, in terms of radiotherapy dose escalation and response prediction in organ preservation approaches for rectal cancer.

【 授权许可】

Unknown