Perception of Stigma and Its Associated Factors Among Patients With Major Depressive Disorder: A Multicenter Survey From an Asian Population

Frontiers in Psychiatry

Pichet Udomratn¹  Jae Nam Bae²  Yi-Ru Fang³  Hong Choon Chua⁴  Shen-Ing Liu⁵  Tom George⁶  Dianne Bautista⁸  A. John Rush⁸  Edwin Chan⁸  Nan Li⁹  Chia-hui Chen^1,10  Manit Srisurapanont^1,11  Gang Chen^1,12  Yan Sun^1,13  Hong Yang^1,13  Jin Pyo Hong^1,14  Ahmad Hatim^1,15  Yun-Ai Su^1,17  Li Wang^1,17  Tian-Mei Si^1,17 

[1]0Department of Psychiatry, Faculty of Medicine, Prince of Songkla University, Songkhla, Thailand

[2]1Department of Psychiatry, Faculty of Medicine, Inha University Hospital, Incheon, South Korea

[3]2Division of Mood Disorders, Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China

[4]3Institute of Mental Health, Woodbridge Hospital, Singapore, Singapore

[5]4Department of Psychiatry, Faculty of Medicine, Mackay Memorial Hospital, Taipei, Taiwan

[6]5North West Specialist Centre, Everton Park, QLD, Australia

[7]6Singapore Clinical Research Institute, Singapore, Singapore

[8]7Duke-National University of Singapore Graduate Medical School, Singapore, Singapore

[9]Department of Epidemiology, Peking University Third Hospital, Beijing, China

[10]Department of Psychiatry, Chang Gung Medical Center and Chang Gung University, Tao-Yuan, Taiwan

[11]Department of Psychiatry, Faculty of Medicine, Chiang Mai University, Muang, Thailand

[12]Department of Psychiatry, Huai’an No.3 People’s Hospital, Jiangsu, China

[13]Department of Psychiatry, Shanxi Dayi Hospital, Taiyuan, China

[14]Department of Psychiatry, University of Ulsan College of Medicine, Asian Medical Center, Seoul, South Korea

[15]Department of Psychological Medicine, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia

[16]Institute of Mental Health, Peking University Sixth Hospital, Beijing, China

[17]National Clinical Research Center for Mental Health Disorders and Key Laboratory of Mental Health, Ministry of Health, Peking University, Beijing, China

关键词: stigma;    Asia;    major depressive disorder;    associated factors;    social support;   

DOI  :  10.3389/fpsyt.2019.00321

来源: DOAJ

【 摘 要 】

Stigma of major depressive disorder (MDD) is an important public health problem. This study aimed to examine the level of perceived stigma and its associated factors in MDD patients in five Asian countries, including China, Korea, Malaysia, Singapore, and Thailand. A total of 547 outpatients with MDD were included from Asian countries. We used the stigma scale of the Explanatory Model Interview Catalogue (EMIC) to assess stigma. The Montgomery–Asberg Depression Rating Scale (MADRS), Symptoms Checklist 90-Revised (SCL-90-R), Fatigue Severity Scale (FSS), Sheehan Disability Scale (SDS), 36-Item Short-Form Health Survey (SF-36), and Multidimensional Scale of Perceived Social Support (MSPSS) were used to assess symptoms, clinical features, functional impairment, health status, and social support. The stigma scores of patients under 55 years old were significantly higher than those equal to or greater than 55 years old (P < 0.001). The stigma scores exhibited significant negative correlation with age; MSPSS scores of family, friends, and others; and SF-36 subscale of mental health, but significant positive correlation with MADRS, FSS, SDS, and SCL-90-R subscale scores of depression, interpersonal sensitivity, obsession–compulsion, psychoticism, and somatization. Multivariate regression analysis revealed that age, SCL-90-R interpersonal sensitivity, obsession–compulsion, psychoticism, MSPSS scores of friends and others, and SF-36 of mental health were significantly associated with the level of perceived stigma. These findings suggest that MDD patients who are young, have a high degree of interpersonal sensitivity and psychoticism, have low health-related quality of life, and have low social support are the target population for stigma interventions in Asia.

【 授权许可】

Unknown