Feasibility and Impact of Adapted Physical Activity (APA) in Cancer Outpatients Beginning Medical Anti-Tumoral Treatment: The UMA-CHAPA Study

Cancers

Alain Delmer¹  Anne Quinquenel¹  Mathilde Brasseur²  Olivier Bouché²  Marine Perrier²  Camille Mazza³  Damien Botsen³  Amélie Lemoine³  Eric Bertin⁴  Hervé Vallerand⁵  Maxime Dewolf⁵  Coralie Barbe⁶ 

[1] Department of Clinical Hematology, CHU Reims, 51100 Reims, France;Department of Gastroenterology and Digestive Oncology, CHU Reims, University of Reims Champagne-Ardenne (URCA), 51100 Reims, France;Department of Medical Oncology, Godinot Cancer Institute, 51100 Reims, France;Department of Nutrition, Endocrinology and Diabetology, CHU Reims, 51100 Reims, France;Department of Pulmonary Medicine, CHU Reims, 51100 Reims, France;Research on Health University Department, University of Reims Champagne-Ardenne (URCA), 51100 Reims, France;

关键词: adapted physical activity;    feasibility;    muscle strength;    anxiety;    cancer patients;   

DOI  :  10.3390/cancers14081993

来源: DOAJ

【 摘 要 】

Adapted physical activity (APA) improves quality of life and cancer outcomes. The aim of this study was to assess the feasibility of an APA program in outpatients beginning medical anticancer treatment. The secondary objective was to assess the impact of APA on fatigue, anxiety, depression, and handgrip strength (HGS). This prospective study was conducted between January and July 2017. Among 226 patients beginning treatment in the unit for a digestive, lung, hematological, or dermatological cancer, 163 were included. Adherence to the APA program was defined as more than or equal to one one-hour session per week for 3 months. The first evaluation was conducted at 3 months (M3), and the second evaluation at 6 months (M6). A total of 163 patients were included (mean age 62.5 ± 14.3); 139 (85.3%) agreed to follow the APA program. At M3, 106 of them were evaluated, of which 86 (81.1%) declared that they had followed the program. Improvement in anxiety was observed at M3 (−1.0 ± 3.2; p = 0.002) but there was no significant change in fatigue or depression. HGS decreased significantly (−1.2 ± 5.5; p = 0.04). The APA program was feasible in cancer outpatients beginning medical anticancer treatment. APA should be part of standard support care.

【 授权许可】

Unknown