Rare non-Wilms' tumors in children

Rare Tumors

Georgios Petrakis¹  Thomas Zaramboukas¹  Emmanouel Hatzipantelis²  Athanassios Tragiannides²  Fani Athanassiadou-Piperopoulou²  Maria Kourti² 

[1] Department of Pathology, Aristotle University of Thessaloniki;Second Department of Pediatrics, Division of Hematology and Oncology, Aristotle University of Thessaloniki;

关键词: rhabdoid tumor, clear cell sarcoma, treatment, renal tumor, children;   

DOI  :  10.4081/rt.2012.e6

来源: DOAJ

【 摘 要 】

We report our institutional experience of the management of 2 cases of rare non-Wilms’ tumors; a rhabdoid tumor in a 17-month old boy and a clear cell sarcoma in a 5-year old girl. The two patients were treated with ifosfamide/ carboplatin/etoposide (ICE) alternating with vincristine/doxorubicin/cyclophosphamide (VDC) and cyclophosphamide/etoposide (CE) alternating with vincristine/doxorubicin/ cyclophosphamide (VDC) and radiotherapy, respectively. Both patients showed full response with no significant adverse events. At 2-year follow up, they are disease and relapse free. Although contemporary treatment regimens are very promising, multicenter collaborative studies are needed in order to define a standard treatment for non-Wilms’ tumors.

【 授权许可】

Unknown