Controlling the Progression of Curvature in Children and Adolescent Idiopathic Scoliosis Following the Administration of Melatonin, Calcium, and Vitamin D

Children

Alexandru Herdea¹  Alexandru Ulici¹  Adham Charkaoui²  Claudiu N. Lungu³  Mihai-Codrut Dragomirescu⁴ 

[1] 11th Department of Pediatric Orthopedics, Carol Davila University of Medicine and Pharmacy, 050474 Bucharest, Romania;Department of Morphological and Functional Sciences, Faculty of Medicine and Pharmacy, Dunărea de Jos University of Galați, 800008 Galați, Romania;Department of Surgery, Clinical Country Emergency Hospital Galati, 800578 Galati, Romania;Pediatric Orthopedics Department, Grigore Alexandrescu Children’s Emergency Hospital, 011743 Bucharest, Romania;

关键词: idiopathic scoliosis;    quality of life;    vitamin D;    melatonin;    calcium;   

DOI  :  10.3390/children9050758

来源: DOAJ

【 摘 要 】

Idiopathic scoliosis affects a severe number of children. Their quality of life and development are also disturbed. Some therapeutic strategies have been developed to control illness progression and to optimize the quality of life. In this perspective, randomized, case-control, interventional study, the impact of using melatonin, calcium, and vitamin D, respectively, on idiopathic scoliosis patients was analyzed. Our preliminary results showed that these drugs positively affected the illness progression quantified by the spine curvature. Patients with idiopathic scoliosis may benefit from a novel treatment by supplementation with vitamin D, calcium, and melatonin.

【 授权许可】

Unknown